ACTIONABILITY KNOWLEDGE REPOSITORY ACTIONABILITY CURATION INTERFACE
Update History
Condition: Multiple Endocrine Neoplasia Type IIB
Gene/Gene Panel: RET
Context: Pediatric
Date
Status
Release
Outcomes-Interventions
Notes
2022/01/14
Released (Under revision)
1.1.3
P
Medullary thyroid carcinoma (GroupA)
Prophylactic thyroidectomy (GroupA) 9CB
Pheochromocytoma (GroupA)
Biochemical Surveillance (GroupA) 11CD
Assertions
Gene Condition Pairs
Suggested Assertion
Final Assertion
RET ⇔ 0008082 MULTIPLE ENDOCRINE NEOPLASIA, TYPE IIB; MEN2B
Strong Actionability
Strong Actionability
2021/09/13
Released
1.1.3
P
Medullary thyroid carcinoma (GroupA)
Prophylactic thyroidectomy (GroupA) 9CB
Pheochromocytoma (GroupA)
Biochemical Surveillance (GroupA) 11CD
Assertions
Gene Condition Pairs
Suggested Assertion
Final Assertion
RET ⇔ 0008082 MULTIPLE ENDOCRINE NEOPLASIA, TYPE IIB; MEN2B
Strong Actionability
Strong Actionability
2021/09/01
Released (Under revision)
1.1.2
P
Medullary thyroid carcinoma (GroupA)
Prophylactic thyroidectomy (GroupA) 9CB
Pheochromocytoma (GroupA)
Biochemical Surveillance (GroupA) 11CD
Edited MONDO ID
2020/04/29
Released
1.1.2
P
Medullary thyroid carcinoma (GroupA)
Prophylactic thyroidectomy (GroupA) 9CB
Pheochromocytoma (GroupA)
Biochemical Surveillance (GroupA) 11CD
Edited MONDO ID
2020/04/29
Released (Under revision)
1.1.1
P
Medullary thyroid carcinoma (GroupA)
Prophylactic thyroidectomy (GroupA) 9CB
Pheochromocytoma (GroupA)
Biochemical Surveillance (GroupA) 11CD
added MONDO ID
2020/04/22
Released
1.1.1
P
Medullary thyroid carcinoma (GroupA)
Prophylactic thyroidectomy (GroupA) 9CB
Pheochromocytoma (GroupA)
Biochemical Surveillance (GroupA) 11CD
added MONDO ID
2020/04/22
Released (Under revision)
1.1.0
P
Medullary thyroid carcinoma (GroupA)
Prophylactic thyroidectomy (GroupA) 9CB
Pheochromocytoma (GroupA)
Biochemical Surveillance (GroupA) 11CD
Internal system migration associated with Gene-Disease scoring groups upgrades.
2019/10/03
Released
1.1.0
P
Medullary thyroid carcinoma (GroupA)
Prophylactic thyroidectomy (GroupA) 9CB
Pheochromocytoma (GroupA)
Biochemical Surveillance (GroupA) 11CD
Internal system migration associated with Gene-Disease scoring groups upgrades.
2019/06/19
Released
1.0.0
P
Medullary thyroid carcinoma
Prophylactic thyroidectomy 9CB
Pheochromocytoma
Biochemical Surveillance 11CD
2019/05/13
In Preparation
N/A
We have begun assessment of the Pediatric context for this topic
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